The Multi-Scale Modelling of Coronary Blood Flow
نویسندگان
چکیده
منابع مشابه
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Coronary blood flow
per tissue mass of all human organs. The resting coronary blood flow is 250 ml min 1 (0.8 ml min 1 g 1 of heart muscle); this represents 5% of cardiac output. Ischaemia results when oxygen demand outstrips supply. Arterial oxygen extraction is 70–80%, compared with 25% for the rest of the body. Therefore, increased oxygen consumption must principally be met by an increase in coronary blood flow...
متن کاملCoronary Blood Flow
In the experimental animal the basic and controversial problem was studied of the influence of cardiac contraction on coronary blood flow. Normally beating hearts were perfused at a constant pressure, and coronary inflow and outflow were determined. In order to assess the role of systole, prolonged periods of ventricular asystole and fibrillation were induced and observations were made of the c...
متن کاملCoronary Collateral Blood Flow
Background. Although aspirin exerts beneficial antiplatelet activity in patients with coronary artery disease, cyclooxygenase blockade produced by aspirin causes a potentially deleterious effect by interrupting endothelial production of prostacyclin. Collateral vessels that develop in response to coronary occlusion display prominent endothelial cell proliferation and undergo vasoconstriction in...
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ژورنال
عنوان ژورنال: Annals of Biomedical Engineering
سال: 2012
ISSN: 0090-6964,1573-9686
DOI: 10.1007/s10439-012-0583-7